Glycemic Response of Amylopectin Containing Drinks
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Area Under the Curve of Glucose
研究概览
简要总结
To quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.
The aim of the study is to quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.
详细描述
Subjects: 9 non-diabetic (HbA1c < 6.5) males aged 30-55 years with body mass indices ranging from 27.5 to 35 kg∙m-2. Individuals with impaired glucose tolerance will be included as long as they are not diagnosed with diabetes and their HbA1c is less than 6.5.
Preliminary Testing: Medical history, weight, height, body composition via dual x-ray absorptiometry (DXA) and glycosylated hemoglobin (HbA1c) measurement.
Protocol: After a 10-hour overnight fast, subjects will complete 3 experimental visits in which they will ingest one of three beverages in a randomized order. During experimental visits subjects will either be given the following 3 experimental drinks:
- Full SP-glucose balance formula (200 kcal)
- Energy smart carbohydrate blend (50 g, 200 kcal)
- Liquid dextrose solution in the form of TRUTOL ® Glucose Tolerance Test Beverage (50 g, 200 kcal)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI 27.5 to 35 kg∙m-2
排除标准
- •Diagnosed diabetes
- •HbA1c > 6.5
- •competitive athletes
- •body weigh change > 3kg during last month
结局指标
主要结局
Area Under the Curve of Glucose
时间窗: 120 minutes
Positive integer of the area under the Curve of glucose
Blood insulin
时间窗: 30, 60 and 120 minutes of the glucose challenge
Blood insulin levels
Area Under the Curve for Insulin
时间窗: 120 minutes
Positive integer of the area under the Curve of insulin
Blood glucose
时间窗: 30, 60 and 120 minutes of the glucose challenge
Blood glucose levels
次要结局
- glucagon(30, 60, and 120 minutes of of the glucose challenge)
- glucagon-like-peptide-1(30, 60, and 120 minutes of the glucose challenge)
- Leptin(30, 60, and 120 minutes of the glucose challenge)
- Adiponectin(30, 60, and 120 minutes of the glucose challenge)
- c-peptide(30, 60, and 120 minutes of the glucose challenge)