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Clinical Trials/CTRI/2019/10/021557
CTRI/2019/10/021557
Completed
未知

Effect of Non-surgical periodontal therapy on Serum level of IL-6 and TNF-α in chronic periodontitis patients with and without Hypothyroidism

RS Indhuja0 sites40 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
RS Indhuja
Enrollment
40
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
February 8, 2016
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
RS Indhuja

Eligibility Criteria

Inclusion Criteria

  • Patients with chronic periodontitis will be diagnosed according to the criteria of 1999 AAP
  • 1\.Attachment loss of \>\= 5 mm at more than 30% of the sites
  • 2\.Patients with bleeding on probing
  • 3\.Patients with \>\= 20 functional teeth
  • Patients with Hypothyroidism:
  • 1\.Based on lab examination of TSH, fT3, fT4 in hypothyroidism patients
  • 2\.Thyroid function test
  • Normal values:
  • 1\.TSH(serum) \-0\.4 to 4\.5 mU/L
  • 2\.fT4 \- 9\.0 to 25\.0 Pmol/L

Exclusion Criteria

  • They suffer from any systemic condition except hypothyroidism that could affect the progress of periodontal diseases.
  • Smokers and former Smokers
  • Alcoholics and former alcoholics
  • Obese, pregnant and lactating woman
  • Subjects over 60 years of age
  • Patients presenting any kind of inflammatory disease within last 3 months
  • They had received professional periodontal treatment during the 6 month period prior to the study.

Outcomes

Primary Outcomes

Not specified

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