Effect of Non-surgical periodontal therapy on Serum level of IL-6 and TNF-Î± in chronic periodontitis patients with and without Hypothyroidism

RS Indhuja0 个研究点目标入组 40 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Patients with chronic periodontitis will be diagnosed according to the criteria of 1999 AAP
•1.Attachment loss of >= 5 mm at more than 30% of the sites
•2.Patients with bleeding on probing
•3.Patients with >= 20 functional teeth
•Patients with Hypothyroidism:
•1.Based on lab examination of TSH, fT3, fT4 in hypothyroidism patients
•2.Thyroid function test
•Normal values:
•1.TSH(serum) -0.4 to 4.5 mU/L
•2.fT4 - 9.0 to 25.0 Pmol/L
•3.fT3 -3.5 to 7.8 Pmol/L
•4.TSH - elevated in hypothyroidism
•5.fT4 and fT3 - reduced in hypothyroidism

•They suffer from any systemic condition except hypothyroidism that could affect the progress of periodontal diseases.
•Smokers and former Smokers
•Alcoholics and former alcoholics
•Obese, pregnant and lactating woman
•Subjects over 60 years of age
•Patients presenting any kind of inflammatory disease within last 3 months
•They had received professional periodontal treatment during the 6 month period prior to the study.

发起方

RS Indhuja