CTRI/2019/10/021557
Completed
未知
Effect of Non-surgical periodontal therapy on Serum level of IL-6 and TNF-α in chronic periodontitis patients with and without Hypothyroidism
RS Indhuja0 sites40 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- RS Indhuja
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with chronic periodontitis will be diagnosed according to the criteria of 1999 AAP
- •1\.Attachment loss of \>\= 5 mm at more than 30% of the sites
- •2\.Patients with bleeding on probing
- •3\.Patients with \>\= 20 functional teeth
- •Patients with Hypothyroidism:
- •1\.Based on lab examination of TSH, fT3, fT4 in hypothyroidism patients
- •2\.Thyroid function test
- •Normal values:
- •1\.TSH(serum) \-0\.4 to 4\.5 mU/L
- •2\.fT4 \- 9\.0 to 25\.0 Pmol/L
Exclusion Criteria
- •They suffer from any systemic condition except hypothyroidism that could affect the progress of periodontal diseases.
- •Smokers and former Smokers
- •Alcoholics and former alcoholics
- •Obese, pregnant and lactating woman
- •Subjects over 60 years of age
- •Patients presenting any kind of inflammatory disease within last 3 months
- •They had received professional periodontal treatment during the 6 month period prior to the study.
Outcomes
Primary Outcomes
Not specified
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