Characterization of bioactive lipids in selected immune cell populations of leukemia patients and their influence on disease progression: a clinically prospective lipidomics approach
Recruiting
- Conditions
- Acute myeloid leukemia and acute lymphocytic leukemia
- Registration Number
- DRKS00032698
- Lead Sponsor
- Carl von Ossietzky Universität Oldenburg, Fakultät VI, Abt. Pharmakologie & Toxikologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Patients with newly diagnosed AML and ALL who have actively consented to the study.
Exclusion Criteria
The following patients are excluded:
Children, persons who are unable to give consent to the study, pregnant women, patients treated exclusively in palliative care and patients who receive or actively seek a hospice place as well as patients after bone marrow transplantation and under CAR-T cell therapy
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection of statistically significant differences in the concentration of bioactive lipid species between leukemia patients and healthy control groups.
- Secondary Outcome Measures
Name Time Method Identification of statistically significant differences in PCR and Western blot analyzes in selected immune cell populations in dependency to lipid-associated proteins.