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Study on nutrition and age-related muscle loss in an Indian populatio

Not Applicable
Conditions
Health Condition 1: M625- Muscle wasting and atrophy, not elsewhere classified
Registration Number
CTRI/2022/12/048031
Lead Sponsor
Institute for Stem Cell Science and Regenerative Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Stable health and ability to be independent/ autonomous

2. with grip strength suggesting sarcopenia and MRI showing sarcopenia

3.with long bone fracture requiring immobilisation

Exclusion Criteria

1. Congenital muscludytrophies

2. Chronic cardiopulmonary insufficiency

3. Severe liver damage (cut-off of transaminase levels) requiring limited protein intake

4. Presence of malignant neoplastic disease (which may cause Cachexia)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quantifying plasma nutrients, IGF-1, IL6, TroponinT, metabolites and lipids from control, sarcopenic and fractured subjectsTimepoint: 24hr
Secondary Outcome Measures
NameTimeMethod
Measuring changes in intestinal microbiota between control, sarcopenic and fractured patients using DNA sequencing of the metagenome.Timepoint: 24hr
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