Marginal Periosteal Pedicle Flap and Platelet Rich Fibrin Barriers for the Treatment of Periodontal Intrabony Defects -Randomized Clinical Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Periodontal Pocket
- Sponsor
- Al-Azhar University
- Enrollment
- 10
- Primary Endpoint
- Intrabony defect
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The use of autogenous graft materials has been recorded to be a gold standard in regenerative therapy. This study directed toward evaluation of two autogenous regenerative materials, marginal periosteal pedicle graft (MPP) and platelet rich fibrin (PRF) as membrane barriers for treating intrabony defects. In spite of its reported significant clinical outcomes, the limited availability of the periosteum makes it necessary to evaluate other autogenous alternatives such as PRF that could offer predictable outcomes.
Detailed Description
Material and methods: 10 patients with sever chronic periodontitis and at least single ≥4 mm intrabony defect had participated in this randomized clinical study. Subjects were randomly divided into2 groups, Group 1(MPP) defect coverage with xenograft defect fill(10 patients),Group 2(PRF) defect coverage with xenograft defect fill(10 patients).Clinical and radiographic measurements were carried out at 3,6 and 9 months postoperatively.
Investigators
Ahmed Y Gamal
Professor of Periodontology Ain Shams University
Al-Azhar University
Eligibility Criteria
Inclusion Criteria
- •No systemic diseases that could influence the outcome of therapy
- •Good compliance for plaque control instructions after initial therapy
- •Vital teeth
- •Had contralateral matched pair of 2- or 3-walled intrabony interproximal defects in premolar or molar teeth
- •Probing pocket depth (PPD)≥6 mm and clinical attachment level (CAL) ≥4mm 6) selected 2- or 3-wall intrabony defect depth ≥ 3 mm as detected in diagnostic periapical radiographs,
Exclusion Criteria
- •Pregnant females and patients presented with opened interproximal contact
Outcomes
Primary Outcomes
Intrabony defect
Time Frame: 9 month after surgery
measurements of intrabony gain from CEJ to base of defect