Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 主要终点
- Clinical Attachment Level
研究概览
简要总结
A clinical and radiographic evaluation of autogenous periosteal pedicle graft in comparison with collagen membrane for management of periodontal intrabony defects.
详细描述
Twenty patients suffering from advanced chronic periodontitis were included in this randomized controlled clinical trial. Each subject contributed matched pairs of two- or three-walled intrabony defects. Each pair of periodontal defects were randomly assigned into the experimental group; periosteal pedicle graft guided tissue membrane or the positive control group; bioresorbable collagen guided tissue regeneration membrane. Clinical and radiographic parameters were recorded at baseline and at 6 months postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 35 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Severe chronic periodontitis patients with at least two sites with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss 2- or 3-wall intrabony defect depth ranging from 3 to 6 mm as detected in periapical radiographs
- •The facial surface of teeth adjacent to the interproximal defect should be free of extensive recession and marginal bone loss, with at least a 4 to 5 mm band of keratinized gingiva to allow for periosteal manipulation
排除标准
- •Pregnant women
- •Subjects had <22 permanent teeth
- •Having any given systemic disease
- •Taking any type of medication and/or antibiotic therapy during the 3 months before the study
- •Received periodontal treatment within the past 12 months
- •Current or former smokers
结局指标
主要结局
Clinical Attachment Level
时间窗: Baseline and 6 months
Estimation of clinical attachment level in chronic periodontitis patients at baseline and 6 months after guided tissue regeneration
次要结局
- Pocket Depth(Baseline and 6 months)
- Bone Defect Area(Baseline and 6 months)
研究者
Noha Ayman Ghallab
Associate Professor of periodontology, faculty of oral and dental medicine
Cairo University