Research on a lactic acid bacterium preparation for stress relief
Not Applicable
- Conditions
- Healthy adults who feel stress
- Registration Number
- JPRN-UMIN000027303
- Lead Sponsor
- Tokushima University
- Brief Summary
1. CP2305 reduced anxiety and sleep disturbance relative to placebo. 2. CP2305 shortened sleep latency and wake time after sleep onset and increased the delta power ratio in the first sleep cycle. 3. CP2305 lowered salivary chromogranin A levels compared with placebo. 4. CP2305 administration attenuated the stress-induced decline of Bifidobacterium spp. and the stress-induced elevation of Streptococcus spp.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
Not provided
Exclusion Criteria
1. Subjects having history of psychiatric or somatic diseases in the past and present. 2. Subjects taking medication at least for three months prior to the enrollment and during the experimental period.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluate the effects of LAB-ingestion on mental and physical conditions at 12 and 24 weeks after the start of intervention by stress-related questionnaires and several measurement items
- Secondary Outcome Measures
Name Time Method Evaluate the effects of LAB-ingestion on sleep quality and abdominal symptoms by questionnaires and related-measurement items