Plasma exchange for lung haemorrhages in leptospirosis
- Conditions
- eptospirosis
- Registration Number
- SLCTR/2018/013
- Lead Sponsor
- Dr Nalaka Herath
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- Not specified
Age 15 to 80 , with lung hemorrhages due to leptospirosis.
Diagnosis of leptospirosis: Patients with a clinical picture suggestive of leptospirosis and confirmed with PCR, MAT or both)
Definition of leptospirosis associated pulmonary hemorrhage: Patient with confirmed leptospirosis presenting with haemoptysis, arterial hypoxemia (Acute Lung Score < 2.5), haemoglobin drop (>10% from the previous value), or diffused alveolar shadows in the chest radiograph. The above manifestations should not have an alternative explanation.
- Chronic kidney disease Stages iii, iv, v
- Chronic hepatitis and liver cirrhosis of any etiology (compensated or decompensated)
- Clinically manifested chronic obstructive airway disease, bronchial asthma, lung fibrosis
- Pregnant women
- Patients aged <15 and > 80 years
- Patients who are haemodynamically unstable for TPE will also be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival [During the hospital stay and at the time of discharge from the hospital ]<br>
- Secondary Outcome Measures
Name Time Method