se of plasma exchange in patients with alcoholic liver failure
- Conditions
- Health Condition 1: K704- Alcoholic hepatic failure
- Registration Number
- CTRI/2019/04/018349
- Lead Sponsor
- Rekha Hans
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Age more than 18 years
2.First episode of de-compensation with APASL ACLF Research Consortium (AARC)- ACLF grade I or II (AARC score <=10)
3.Cause of ACLF being alcohol related liver disease
4.No evidence of active infection
5.Willing to give informed consent for the procedure(In patients who are incompetent to consent,consent shall be taken from the surrogate)
1.Pregnancy
2.Causes of ACLF other than alcohol
3.Co-existing HCC or extra-hepatic malignancy
4.Microbiological or radiological evidence of active infection
5.Active hemorrhage
6.Extra-hepatic multi-organ failure (>=3 organ failures)
7.APASL-AARC score >10
8.Known allergy to Plasma, Protamine or Heparin.
9.Mechanically ventilated patients
10.Severe preexisting cardiopulmonary disease
11.Requiring inotropic support
12.Renal failure requiring dialysis
13.Severe systemic illness like HIV
14.Post liver transplant patients
15.Death within 24 hours of presentation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method