Neurodevelopmental Outcome of the Infants With Transient Hypothyroxinemia of Prematurity in Newborn Intensive Care Unit
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Transient Hypothyroxinemia of Prematurity
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Long-term Neurodevelopment
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
• Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant. This study aims to evaluate the neurological development of infants with transient premature hypothyroxinemia (THoP).
Investigators
Seda Yilmaz Semerci
Principal investigator
Kanuni Sultan Suleyman Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •newborn infants who were born at 28-36 gestational weeks
- •Infants who were hospitalized in the neonatal intensive care unit
- •Infants with transient hypothyroxinemia of prematurity
Exclusion Criteria
- •Newborns with maternal thyroid disease,
- •Severe intracranial issues,
- •Chromosomal and congenital anomalies,
- •Infants older than 36 gestational weeks
Outcomes
Primary Outcomes
Long-term Neurodevelopment
Time Frame: 5 years
'Ages And Stages Questionnaires' (ASQ) 'Ages And Stages Questionnaires: Social-Emotional' (ASQ:SE) Developmental Screening Tests evaluates the areas of communication, fine motor, gross motor, problem-solving and personal-social development. ASQ score differs 0-60 and results are interpreted in three group according to the gained points as normal, risky, and follow-up required.