acetylcysteine for LPRD

Not Applicable

Completed

• Conditions: Diseases of the digestive system

• Registration Number: KCT0004099
• Lead Sponsor: Inje University Ilsan Paik Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. symptoms of LPRD : globus (a sensation of a lump in the throat), throat clearing, hoarseness, postnasal drip (PND) sense and cough
2. reflux symptom index (RSI) greater than 13
3. reflux finding scores (RFS) greater than 7

Exclusion Criteria

patients with acute or chronic sinusitis or with symptoms of upper respiratory infection at initial visit, patients with lower respiratory disease such as asthma, chronic obstructive pulmonary disease, pneumonia, or lung cancer, patients with organic lesions in the pharynx, larynx, or oral cavity such as malignancy, significant hypertrophy of palatine or lingual tonsil, or huge vallecular cyst, patients who had psychiatric history such as depression or insomnia or those taking psychiatric medication, patients older than 70 years, younger than 20 years, or pregnant, patients currently taking PPI

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
improvement of reflux symptom index

Secondary Outcome Measures

Name	Time	Method
improvement of reflux finding score