Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to Emergencies. Prospective and Multicentric Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 579
- 试验地点
- 3
- 主要终点
- meningitis (either viral or bacterial) or absence of meningitis
研究概览
简要总结
Meningitis are serious infections. Evidenced by high rates of mortality and sequelae. However, these diseases have a relatively small impact. Also physician services Home Emergencies they must be vigilant, alert, for clinical signs to be suspected meningitis. Indeed, it is only after this essential clinical milestone that will be carried out a lumbar puncture which will confirm the diagnosis and to quickly begin treatment.
Unfortunately, if recent studies can improve the therapeutic management of patients with meningitis, no study was interested in yet fundamental step of diagnosis.
It seems therefore necessary to achieve a prospective clinical study to reassess the adequacy of the clinical signs in the diagnosis of meningitis. The ideal would be to achieve a predictive clinical score of the presence or absence of meningitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •May be included in the study two groups of patients:
- •*On the one hand, those in which will be carried out a lumbar puncture. Ideally, all patients in whom the examination is envisaged will be included. The logistics must allow inclusion rate as high as possible (see below).
- •So, are included in this group, patients for which the following criteria are met:
- •Over 15 years patient and 3 months,
- •Admission to the emergency for less than 6 hours
- •Realization of a proposed lumbar puncture,
- •Information sheet given. *On the other hand, those in whom it is not intended to be carried by lumbar puncture, but for which the clinical picture present on admission makes relevant for clinical signs of meningitis.
- •So, are included in this group, patients for which the following criteria are met:
- •Over 15 years patient and 3 months,
- •Admission to the emergency for less than 6 hours
- •At least one of the following 5 clinical signs motivating consultation and / or present on admission:
- •fever (measured temperature above 38 ° C)
- •headache,
- •vomiting,
- •stiff neck,
- •vigilance disorders,
- •Information sheet given.
排除标准
- •Patient who underwent neurosurgery recent (within the month before admission).
结局指标
主要结局
meningitis (either viral or bacterial) or absence of meningitis
时间窗: Until 2 days
次要结局
未报告次要终点