Prevalence of Dyschromatopsia in Glaucoma Patients

Withdrawn

• Conditions: Open Angle Glaucoma

• Registration Number: NCT01994564
• Lead Sponsor: Massachusetts Eye and Ear Infirmary

Brief Summary

Glaucoma is a progressive disease resulting in loss of retinal nerve cells and their axons (retinal nerve fibers). Retinal nerve fibers are ordered in a special manner when they enter the optic nerve. Hence, damage to the retinal nerve fibers by glaucoma results in visual field defects at certain locations. Furthermore, the retinal nerve fiber layers from different receptors for different colors are ordered in a special manner as well. Thus, it is possible that glaucomatous damage causes color vision dysfunction (dyschromatopsia).

At the moment there is disagreement whether dyschromatopsia occurs at early- to mid-stage or only in end-stage glaucoma.

By testing color vision in glaucoma patients the prevalence of dyschromatopsia in glaucoma and in different stages of the disease will be investigated.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-07
• Study Start: 2012-11
• Study First Submitted: 2013-11-19
• Study First Submitted QC: 2013-11-19
• Last Update Submitted: 2013-11-19
• Study First Posted: 2013-11-26
• Last Update Posted: 2013-11-26
• Primary Completion: 2013-12
• Study Completion: 2014-01

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• diagnosis of open angle glaucoma
• visual acuity >/= 20/50
• age >/= 18 (no upper limit)
• male or female gender

Exclusion Criteria

• other type of glaucoma
• age <18
• other retinal disease (e.g. age related macular degeneration)
• other disease affecting the optic nerve or the retinal nerve fibers
• known color blindness

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Result from Ishihara Test	Visit 1	Color vision will be tested once by Ishihara plates. Both eyes will be tested separately.

Secondary Outcome Measures

Name	Time	Method
Glaucoma stage	Visit 1	Visual field will be tested with 30-2 Humphrey visual field full threshold test. Visual field defects will we graded following the Hodapp-Anderson-Parrish Scale (Hodapp E, Parrish RK, Anderson DR. Classification of Defects in Clinical Decisions in Glaucoma. St. Louis: Mosby, 1993:52-61).

Trial Locations

Locations (1)

Massachusetts Eye & Ear Infirmary; 🇺🇸 Boston, Massachusetts, United States