Comparison of the analgesic effect of oral Meloxicam and Diclofenac after knee arthroplasty

Phase 3

Recruiting

• Conditions: Osteoarthritis of knee.; Osteoarthritis of knee, unspecified; M17.9

• Registration Number: IRCT20221126056613N4
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

Diagnosis of knee osteoarthritis based on the scales of the American Society of Anesthesiology
Candidate for knee joint replacement surgery
American Society of Anesthesiology grade 1 and 2 physical status patients
No history of corticosteroid or hyaluronic acid injections into the joint during the past three months
No history of knee surgery or interventional treatment

Exclusion Criteria

Age less than 18 years
pain reliever use in the past 7 days
Blood and coagulation disorders
Severe heart-liver and kidney failure
Any absolute and relative contraindications to the use of drugs during the study
Nervous disorders and the inability to accurately perceive the sensation of pain
Pregnancy and breastfeeding
Patients using the intravenous form of morphine

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity of pain. Timepoint: Pain intensity will be measured at 24, 48 and 72 hours after the operation. Method of measurement: The intensity of pain after the operation of the patients will be measured using a visual analog index and scoring method from 0 (no pain) to 10 (unbearable pain).