Effects of high flow nasal oxygen cannula on treatment outcomes in patients with chronic obstructive lung disease with acute exacerbatio

Phase 2

Recruiting

• Conditions: COPD with acute exacerbation; High flow nasal oxygen cannula; Chronic obstructive lung disease; COPD; Acute exacerbation; Treatment outcomes

• Registration Number: TCTR20150921003
• Lead Sponsor: Ratchadaphiseksomphot Endowment Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-21
• Study Completion: 2016-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Age ≥40 year
2. Diagnosis of COPD
3. Acute exacerbation
4. Hypoxemia

Exclusion Criteria

1. Acut hypercapnia
2. Need for non-invasive or invasive mechanical ventilation
3. Severe hemodynamic instability
4. Severe comorbidities (Cardiovascular, Cerebrovascular disease)
5. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Requirement for non-invasive and invasive mechanical ventilation in each group 72 hours Time to event

Secondary Outcome Measures

Name	Time	Method
evel of partial pressure of oxygen (PaO2) in arterial blood gas 72 hours Blood puncture,Level of partial pressure of carbon dioxide (PaCO2) in arterial blood gas 72 hours Blood puncture,Change in respiratory rate (RR) 72 hours Observation,Change in dyspnea score and comfort score 72 hours Interview,Length of stay Until hospital discharge Observation