Identifying new tumour markers in oesophageal (gullet) and gastroesophageal (stomach/gullet) cancers
Not Applicable
Completed
- Conditions
- Oesophageal cancerCancer
- Registration Number
- ISRCTN11063656
- Lead Sponsor
- niversity of Dundee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
1. 18 years of age or older
2. Willing and able to provide written informed consent
3. Histologically confirmed oesophageal or gastroesophageal junctional adenocarcinoma.
4. Able to provide a tumour biopsy sample as per protocol requirements
Exclusion Criteria
1. Concurrent systemic anti-cancer treatment and/or radiotherapy (participants undergoing cancer surgery are eligible.)
2. Any significant medical condition that in the opinion of the Principal Investigator (PI) would impair the ability of the participant to complete the requirements of the protocol
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eoantigen profiles for individual patients with oesophageal or gastroesophageal junction adenocarcinomas measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) of tumour biopsies taken at Day 1 and a maximum of 3 further optional research biopsy samples may be collected between day 1 and week 18, timings will vary for participants for these biopsies to fit in with their standard care procedures.
- Secondary Outcome Measures
Name Time Method