“A COMPARATIVE STUDY ON THE EFFICACY OF ABHYAṄGA AND PÄ€NA OF NIRGUṆḌI-TAILA IN THE MANAGEMENT OF SANDHIGATA-VÄ€TA IN PURVIEW OF “bÄhyÄbhyantarataḥsnÄ“hairasthimajjagataá¹jayÄ“tâ€,
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in the Visual Analogue Scale (VAS),and Womac scale.
研究概览
简要总结
NEED OF STUDY:
Therapeutically in present era multiple regimens have been described in different classics of Āyurveda, but potent and durable results are not found as a result of non-eradication of the root cause. Hence its special emphasis or searching for more effective and suitable drug for osteoarthritis should be done.
Ä€yurveda provides the best alternative option for the management of osteoarthritis. According to classical text Aá¹£á¹Äá¹…gahá¹›daya, sandhigata vÄta is managed by repeated use of snehana, swedana, basti and má¹›uduvirecana therapies.
Ä€cÄrya SuÅ›ruta has mentioned snehana, upanÄha, agnikarma, bandhana and unmardana for the treatment for sandhigata vÄta.Ä€cÄrya Caraka has mentioned snehana, swedana, má¹›duvirecana, bastikarma for the treatment of vÄtavyÄdhi.One should overcome the vÄta located in asthi and majjÄ by applying unction externally as well as internally.
Ä€gni will have to be evaluated especially while giving the sneha internally. But for proper assessment of results using the principles of statistics in the feild of research, stable dose will be more suitable. Thus Nirguṇá¸i taila will be given in same quantity in all patients but as per the status of their Ägni, time of consumption of food will be managed accordingly.
Here ‘Nirguṇá¸i taila’ abhyaá¹…ga and ‘Nirguṇá¸i taila’ pÄna are selected for this study.
‘Nirguṇá¸i taila’ is mentioned in ‘Caraka SamhitÄ’cikitsÄsthÄna chapter 28vÄtavyÄdhiprakaraṇa for both internal and external use.
Above mentioned drugs are easily available, effective and easy to administer in the patients. Also internal as well as external use of sneha will be effective in sandhigata vÄta in comparison to mere kwath preparations which are basically dry in their nature.
These are the basic reasons for the selection of these abovementioned drugs for present clinical trial.
Research question: Is there any difference between the efficacy of Nirguṇá¸i taila abhyaá¹…ga and Nirguṇá¸i taila pÄna in the management of sandhigata vÄta ?
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with clinical feature of sandhigata vÄta as described in classic texts.
- •Patients with chronicity of less than 10 years.
排除标准
- •Patients who are below age of 30 year or over age of 60 year.
- •Patients having severe joint deformities.(permanent joint deformities) Patients suffering from whole body paralysis (Quadriplegia).
- •Patients having any type of arthropathy other than osteoarthritis such as neoplasm of spine, ankylosis spondylitis, traumatic arthritis , pyogenic osteomyelitis, gout etc.
- •Patients having associated cardiac disease, tuberculosis, malignant .
- •Patients contraindicated for snehapÄna and abhyaá¹…ga in Ä€yurveda classical text.
结局指标
主要结局
Changes in the Visual Analogue Scale (VAS),and Womac scale.
时间窗: 7th day, 14th day, 21th day, 30th day
次要结局
- Change in ESR,CBC,Lipid Profile(Before treatment and after treatment)