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临床试验/JPRN-UMIN000032826
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Cohort study of osteoarthritis by MRI 3D analysis (Kanagawa Knee Study) - Cohort study of osteoarthritis by MRI 3D analysis (Kanagawa Knee Study)

Tokyo Medical and Dental University0 个研究点目标入组 573 人开始时间: 2018年9月1日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
入组人数
573

研究概览

简要总结

MME was unchanged in KL grade 1 and KL grade 0, whereas it increased slightly in KL grade 2 and increased moderately in KL grade 3. Cartilage thickness first decreased in the medial tibial region in KL grade 2 subjects and in the medial femoral region in KL grade 3. Cartilage thinning occurred in the anterior central medial femoral subregion and in the anterior and middle external medial tibial subregions in KL grade 1, whereas it diffusely expanded in early and moderate knee OA.

研究设计

研究类型
Interventional

入排标准

年龄范围
30years-old 至 79years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • 1) People who cannot attend the second MRI examination one year later. 2) People who cannot obtain informed consent due to cognitive impairment. 3) People who cannot undergo MRI examination due to claustrophobia. 4) People who cannot undergo MRI examination due to metal in the body. 5) People with a history of surgery in either knee. 6) People who visited hospital for injury in either knee for more three months. 7) People who have osteoarthritis or history of fracture in either lower extremity. 8) People who are diagnosed as collagen disease such as rheumatoid arthritis. 9) People who have any knee injection or arthrocentesis. 10) People who are poor general condition. 11) People who are pregnant or possible pregnant. 12) People who have a consciousness of doing vigorous sports such as full marathon, triathlon, weight lifting. 13) People for whom involved doctors decide as not appropriate to participate in the study.

研究者

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