Validation of MRI imaging of CMC1 osteoarthritis using histological characterization of involved tissues

Recruiting

• Conditions: osteoarthritis; wear-and-tear of joints; 10043237

• Registration Number: NL-OMON35705
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

CMC1 osteoarthritis patients scheduled for trapezectomy or joint replacement at the Erasmus MC.

Exclusion Criteria

Patients will be excluded if they have any contra indications for MRI scanning, such as the presence of a pacemaker, metals in their body or pregnancy.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Index test: MRI<br /><br>Reference test: histological characterization of bone, cartilage and synovial<br /><br>tissue</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>A number of characteristics thumb functioning such as strength, range of<br /><br>motion, coordination and the ability to perform daily life task with the hand. </p><br>