The value of narrowband imaging with magnifying endoscopy in the surveillance of patients with intestinal metaplasia and dysplasia of the gastric mucosa

Recruiting

• Conditions: premalignant gastric lesions; 10017990; 10017991

• Registration Number: NL-OMON30828
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 130

Inclusion Criteria

Patients undergoing a surveillance endoscopy because of a previous diagnosis of intestinal metaplasia or dysplasia of the gastric mucosa
Patients with gastric intestinal metaplasia or dysplasie diagnosed after the start of the study

Exclusion Criteria

Coagulopathy uncorrected at the time of endoscopy or thrombocytopenia

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The number of detected lesions with histological proven intestinal metaplasia<br /><br>or dysplasia after NBI-ME as compared to the number of detected lesion with<br /><br>histological proven intestinal metaplasia or dysplasia after conventional<br /><br>endoscopy. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correspondence between serologic markers (pepsinogen I, II and gastrin 17) and<br /><br>H. pylori data and histology</p><br>