EUCTR2006-007011-24-IT
Active, not recruiting
Not Applicable
Assessment of endothelial function in patients with psoriasis before and after Etanercept treatment - ND
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI0 sites40 target enrollmentFebruary 14, 2007
DrugsENBREL
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- moderate to severe psoriasis
- Sponsor
- POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
- Enrollment
- 40
- Status
- Active, not recruiting
- Last Updated
- 14 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. age 18 years 2\. active but clinically stable plaque psoriasis resistant to traditional treatments 3\. involvement of at least 10 percent of the body surface area 4\. minimal psoriasis area\-and\-severity index 21 of 10 indicating moderate to severe psoriasis during the screening period 5\. at least once previous phototherapy or systemic psoriasis therapy or eligibility for such therapy
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •1\. pregnancy and nursing 2\. guttate, erythrodernic, or pustular psoriasis at the time of screening 3\. previous treatment with etanercept or anti\-TNF antibodies 4\. previous treatment with anti\-CD4 antibodies or interleukin\-2\-diphtheria\-toxin fusion protein within the previous six months 5\. previous treatment with biologic or investigational drug, psoralen\-ultaviolet A phototherapy, systemic corticosteroids, or systemic psoriasis therapy within the previous four weeks 6\. previous treatment with ultraviolet B phototherapy, topical corticosteroids, vitamin A or D analogues, or anthralin within the previous two weeks antibiotic treatment within the previous week 7\. other inflammatory, systemic or skin disease 8\. recent vaccination
Outcomes
Primary Outcomes
Not specified
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