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Clinical Trials/NCT00931151
NCT00931151
Completed
Not Applicable

Effects of Dietary Protein on Undesirable Postprandial Events in Overweight Subjects

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement1 site in 1 country10 target enrollmentStarted: April 2009Last updated:
ConditionsOverweight

Overview

Phase
Not Applicable
Status
Completed
Enrollment
10
Locations
1
Primary Endpoint
Endothelial dysfunction

Overview

Brief Summary

Dietary protein differing by their amino acid composition could modulate undesirable metabolic and functional responses to a meal rich in saturated fat and sugars. This study aims at examining the specific effects of dairy protein with different cysteine contents on the postprandial undesirables effects elicited by the ingestion of a high fat meal in overweight subjects.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Basic Science
Masking
None

Eligibility Criteria

Ages
18 Years to 50 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • BMI between 25 and 30
  • Waist circumference \> 94 cm

Exclusion Criteria

  • Allergy to milk protein
  • Abusive drug consumption
  • Hypertension, diabetes
  • High level of physical activity

Outcomes

Primary Outcomes

Endothelial dysfunction

Time Frame: 0-2-4-6 hours (after meal ingestion)

Secondary Outcomes

  • Postprandial inflammation(0-0.5-1-1.5-2-3-4-6 hours (after meal ingestion))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Robert Benamouzig

Professor

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Study Sites (1)

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