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Clinical Trials/NCT02619409
NCT02619409
Completed
Not Applicable

Evaluation of the Duration of Bupivacaine Spinal Block as the Primary Anesthetic for Orthopedic Procedures With and Without Epinephrine Wash

Medical University of South Carolina1 site in 1 country30 target enrollmentFebruary 11, 2016

Overview

Phase
Not Applicable
Intervention
EPI75 group
Conditions
Arthropathy of Hip
Sponsor
Medical University of South Carolina
Enrollment
30
Locations
1
Primary Endpoint
Duration of Sensory Block
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block. The epinephrine wash may prolong the duration of the block, and if it does, to what extent?

Registry
clinicaltrials.gov
Start Date
February 11, 2016
End Date
October 20, 2016
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Eric Bolin

Assistant Professor

Medical University of South Carolina

Eligibility Criteria

Inclusion Criteria

  • 18 years of age or older
  • Patients scheduled for total hip or knee replacement

Exclusion Criteria

  • Patients taking anticoagulation
  • Infection at or near the intended needle insertion site
  • Patients with sacral decubitus ulcer at or near the intended needle insertion site aortic stenosis
  • Complex spine anatomy
  • ASA class greater than III
  • Failed SAB as determined by the staff anesthesiologist

Arms & Interventions

EPI75 group

The EPI75 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.075 cc, and sterile saline 0.025%.

Intervention: EPI75 group

Bupivacaine Only

The bupivacaine only group will receive bupivacaine 0.5% 3cc plus sterile saline 0.1cc.

Intervention: Bupivacaine Only

EPI25 group

The EPI25 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.025cc, and sterile saline 0.075cc.

Intervention: EPI25

EPI50 group

The EPI50 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.05cc, and sterile saline 0.05cc.

Intervention: EPI50 group

EPI100 group

The EPI100 group will receive bupivacaine 0.5% 3cc, and epinephrine 1:1000 0.1cc

Intervention: EPI100 group

Outcomes

Primary Outcomes

Duration of Sensory Block

Time Frame: 12 hours

Duration of the sensory block at the T12 dermatome will be assessed in the post operative phase

Duration of Motor Block

Time Frame: 12 hours

(hip felxion) of the non operative leg

Study Sites (1)

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