Evaluation of the Duration of Bupivacaine Spinal Block as the Primary Anesthetic for Orthopedic Procedures With and Without Epinephrine Wash
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Duration of Sensory Block
研究概览
简要总结
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block. The epinephrine wash may prolong the duration of the block, and if it does, to what extent?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age or older
- •Patients scheduled for total hip or knee replacement
排除标准
- •Patients taking anticoagulation
- •Infection at or near the intended needle insertion site
- •Patients with sacral decubitus ulcer at or near the intended needle insertion site aortic stenosis
- •Complex spine anatomy
- •ASA class greater than III
- •Failed SAB as determined by the staff anesthesiologist
研究组 & 干预措施
EPI75 group
The EPI75 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.075 cc, and sterile saline 0.025%.
干预措施: EPI75 group (Drug)
Bupivacaine Only
The bupivacaine only group will receive bupivacaine 0.5% 3cc plus sterile saline 0.1cc.
干预措施: Bupivacaine Only (Drug)
EPI25 group
The EPI25 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.025cc, and sterile saline 0.075cc.
干预措施: EPI25 (Drug)
EPI50 group
The EPI50 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.05cc, and sterile saline 0.05cc.
干预措施: EPI50 group (Drug)
EPI100 group
The EPI100 group will receive bupivacaine 0.5% 3cc, and epinephrine 1:1000 0.1cc
干预措施: EPI100 group (Drug)
结局指标
主要结局
Duration of Sensory Block
时间窗: 12 hours
Duration of the sensory block at the T12 dermatome will be assessed in the post operative phase
Duration of Motor Block
时间窗: 12 hours
(hip felxion) of the non operative leg
次要结局
未报告次要终点
研究者
Eric Bolin
Assistant Professor
Medical University of South Carolina