Efficacy of Benzydamine Hydrochloride in Reducing Postoperative Sore Throat after General Anesthesia with Endotracheal Tube: a Randomized Controlled Trial

Phase 4

• Conditions: Postoperative sore throat; benzydamine hydrochloride, endotracheal tube, general anesthesia, postoperative sore throat

• Registration Number: TCTR20210610002
• Lead Sponsor: Rajavithi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-10
• Study Completion: 2022-04-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1. Patients undergoing surgery under general anesthesia with oral endotracheal intubation, elective surgery.
2. The duration of the surgery is not more than 4 hours.
3. ASA Physical status 1-3

Exclusion Criteria

1. Pregnant women or patients at risk for aspiration pneumonia
2. The patient has a history or has been assessed as difficult intubation
3. The patient undergoing head, face, and neck surgery
4. Currently has a sore throat or have a sore throat within 1 week before surgery
5. Allergy to benzydamine hydrochloride or other NSAIDs.
6. On steroids or lidocaine before surgery
7. Has limited communication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The incidence of postoperative sore throat The first 24 hours after surgery Patient reported outcome with a four-point verbal categorical rating scale.

Secondary Outcome Measures

Name	Time	Method
Side effects of benzydamine hydrochloride The first 24 hours after surgery Patient reported outcome