EFFICACY OF BENZYDAMINE HYDROCHLORIDE, A LOCALLY ACTING ANTI INFLAMMATORY SOLUTION, GARGLES, ON POST OPERATIVE COMPLICATIONS LIKE SORE THROAT, HOARSENESS OF VOICE AND COUGH FOLLOWING TRACHEAL INTUBATION.
Phase 4
- Conditions
- Health Condition 1: null- Patients belonging in the age group of 16-60 undergoing surgery under general anesthesia
- Registration Number
- CTRI/2016/04/006792
- Lead Sponsor
- OKMANYA TILAK MUNICIPAL MEDICAL COLLEGE AND GENERAL HOSPITAL SIO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Patients undergoing general surgical, gynaecological and orthopaedic
procedures under General Anaesthesia.
ASA grade I and II.
Duration of surgery 1-3 hours.
Patients with as well as without Naso-gastric (Ryleâ??s tube) in situ. (inserted post induction, intraoperatively)
Exclusion Criteria
Unwilling Patients.
Mallampatti classification > 2.
Patients with preoperative sore throat or URTI within last 7 days of
surgery.
Known allergies to Benzydamine Hydrochloride.
All pregnant mothers.
Patients with gastro-esophageal reflux/ regurgitation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sore throat, cough and HoarsenessTimepoint: 0, 2, 4, 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method Intracuff pressure, heart rate and blood pressureTimepoint: Intraoperatively every 15 minutes;Side effectsTimepoint: intra and postoperatively