Effect of Dual-task Exercise on Cognitive and Physical Function in the Elderly With Mild Cognitive Impairment: a Randomized Controlled Trial
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Cognitive Dysfunction
- 发起方
- Seoul National University Boramae Hospital
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Dual task cost in 10-meter walking test
- 状态
- 已完成
- 最后更新
- 2年前
概览
简要总结
The purpose of this study is to investigate the effect of the dual task exercise program on cognitive and physical function in the elderly with mild cognitive impairment.
详细描述
All participants provided written informed consent before study participation. A total of 12 community-dwelling participants were randomized either to the exercise group or to the control group. The exercise group underwent 8-week, 3 times a week, 60-minute group exercise sessions, which were comprised of moderate-to-high intensity exercise and simultaneous cognitive tasks. They also performed moderate-intensity home aerobic exercises for at least 60 minutes per week. The control group performed 60-minute light intensity home exercise, 4 times a week for 8 weeks.
研究者
Cha Hee Young
Principal Investigator
Seoul National University Boramae Hospital
入排标准
入选标准
- •a score on the Korean Montreal Cognitive Assessment (MoCA-K) of 25 points or below
- •aged 65 or more
- •no physical or medical problem which impairs moderate to vigorous physical activity
排除标准
- •uncontrolled or unstable cardiovascular disease
- •malignancy affecting general condition
- •musculoskeletal problems affecting motor performance
- •speech and hearing impairment
- •other organic brain diseases
结局指标
主要结局
Dual task cost in 10-meter walking test
时间窗: immediately after the 8-week intervention
Participants completed both single-task (ST) and dual-task (DT) tests at baseline and post-intervention. For a ST condition, participants performed motor task only such as 10-meter walking test (10MWT). 10MWT is a performance measure used to assess walking speed over a short distance. For a DT condition, participants performed 10MWT while performing serial 3 simultaneously. Serial 3 is descending subtraction task, where the patient counts down from one hundred by threes. In the DT condition, participants were given no instruction regarding the prioritization of one task over the other. We calculated 10MWT gait speed in both conditions. Dual task cost(DTC) were calculated as a percentage as follows: (%DTC) = \[dual task duration or speed - single task duration or speed\] / \[single task duration or speed\] \* 100%. The lower DTC indicates efficiency in cognitive-motor interplay and good dual task ability.
Dual task cost in Timed up and go (TUG)
时间窗: immediately after the 8-week intervention
Participants completed both single-task (ST) and dual-task (DT) tests at baseline and post-intervention. For a ST condition, participants performed motor task only such as Timed up and go (TUG). TUG measured the time of taking to rise from a chair, walking three meters, turning around 180 degrees, walking back to the chair, and sitting down while turning 180 degrees. For a DT condition, participants performed TUG while performing serial 3 simultaneously. Serial 3 is descending subtraction task, where the patient counts down from one hundred by threes. In the DT condition, participants were given no instruction regarding the prioritization of one task over the other. We calculated TUG duration in both conditions. Dual task cost(DTC) were calculated as a percentage as follows: (%DTC) = \[dual task duration or speed - single task duration or speed\] / \[single task duration or speed\] \* 100%. The lower DTC indicates efficiency in cognitive-motor interplay and good dual task ability.
次要结局
- Godin Leisure Time Exercise Questionnaire (GLTEQ)(immediately after the 8-week intervention)
- Computerized cognitive test(digit span test, visual learning test, verbal learning test, the Stroop Color and Word test, Boston naming test, trail making test, and verbal fluency test)(immediately after the 8-week intervention)
- International Physical Activity Questionnaires Short form (IPAQ)(during intervention (8 weeks))
- Metabolic Equivalent Task (MET) minutes per week(during intervention(8 weeks))
- Exercise Identity Scale (EIS)(immediately after the 8-week intervention)
- Psychological Need Satisfaction in Exercise Scale (PNSE)(immediately after the 8-week intervention)
- Korean Montreal Cognitive Assessment (MoCA-K)(immediately after the 8-week intervention)
- Korean Mini Mental Status Examination (K-MMSE)(immediately after the 8-week intervention)
- Falls Efficacy Scale (FES)(immediately after the 8-week intervention)
- Activities-specific Balance Confidence (ABC)(immediately after the 8-week intervention)
- Grip strength(immediately after the 8-week intervention)
- Korean version of Physical Activity Scale for the Elderly (K-PASE)(during intervention(8 weeks))
- Short Physical Performance Battery (SPPB)(immediately after the 8-week intervention)
- Berg Balance Scale (BBS)(immediately after the 8-week intervention)
- Bioelectrical Impedance Analysis(immediately after the 8-week intervention)