Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.

Completed

• Conditions: Healthy; Obstructive Sleep Apnea

• Registration Number: NCT00291993
• Lead Sponsor: Regional Hospital Holstebro

Brief Summary

Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension. Nocturnal hypoxia, hypercapnia and acidosis stimulate chemoreceptors and presumably increased secretion of vasoactive hormones which might be responsible for hypertension in these patients.

The aim of this study is to measure the secretion of vasoactive hormones at night and to analyse the relationship between vasoactive hormones, oxygen saturation and the blood pressure at night.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-01
• Study First Submitted: 2006-02-13
• Study First Submitted QC: 2006-02-13
• Study First Posted: 2006-02-15
• Status Verified: 2008-04
• Last Update Submitted: 2008-04-17
• Last Update Posted: 2008-04-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Male and female Age 20-65 Obstructive sleep apnea

Exclusion Criteria

Drug or alcohol abuse Pregnancy or breast feeding Cancer Clinical signs or history of disease in the heart, lungs, kidney or endocrine organs Abnormal laboratory tests Albuminuria or glucosuria Aterial hypertension for healthy subjects

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (3)

Department of Medical Research, Holstebro Hospital; 🇩🇰 Holstebro, Ringkoebing County, Denmark

Department of Medical Research; 🇩🇰 Holstebro, Denmark

Holstebro Hospital, Department of Medical Research; 🇩🇰 Holstebro, Denmark