Impact of Early Mobilization on SAH Patients Physiological Parameters
- Conditions
- Subarachnoid Hemorrhage
- Interventions
- Device: lung ultrasoundDevice: Transcranial DopplerDevice: near-infrared spectroscopy (NIRS)Device: clinical examination
- Registration Number
- NCT06286683
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Brief Summary
The aim of the study is to evaluate the physiological response to out-of-bed mobilization in patients admitted to the intensive care unit for subarachnoid hemorrhage. More specifically, the aim is to measure the impact on cerebral perfusion, lung aeration, cardiovascular and respiratory parameters.
- Detailed Description
In patients with subarachnoid hemorrhage, the mobilization strategy has been little studied. Several studies have already evaluated the consequences of mobilization in bed. Because of the deleterious consequences of prolonged bed rest, and in line with recommendations, practices have evolved towards early out-of-bed mobilization, which has shown benefits. However, the physiological consequences of out-of-bed mobilization have not yet been assessed. The aim of this study is to measure the impact of early out-of-bed mobilization of patients admitted for SAH on neuro-cardio-pulmonary physiological parameters.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 100
Age ≥ 18 years
- Aneurysmal SAH
- Severity score World Federation Neurological Surgeons I to IV
- Secured aneurysm
- Eligible for their first early mobilization
- Sedated patient
- Disturbed alertness, coma
- Unsecured aneurysm
- Patients under legal protection (guardianship, curatorship, safeguard of justice)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients admitted to intensive care near-infrared spectroscopy (NIRS) Patients admitted to intensive care for aneurysmal subarachnoid hemorrhage (SAH) and eligible for their first out-of-bed mobilization Patients admitted to intensive care lung ultrasound Patients admitted to intensive care for aneurysmal subarachnoid hemorrhage (SAH) and eligible for their first out-of-bed mobilization Patients admitted to intensive care clinical examination Patients admitted to intensive care for aneurysmal subarachnoid hemorrhage (SAH) and eligible for their first out-of-bed mobilization Patients admitted to intensive care Transcranial Doppler Patients admitted to intensive care for aneurysmal subarachnoid hemorrhage (SAH) and eligible for their first out-of-bed mobilization
- Primary Outcome Measures
Name Time Method Impact on lung aeration at T0 before initiation of out-of-bed mobilization, and 15 minutes after moving to the chair. Lung Ultrasound Score by lung ultrasound, Ranging from 0 (normal lungs) to 36 (worst case scenario).
- Secondary Outcome Measures
Name Time Method Impact on neurological examination At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. Glasgow Coma Scale score (scored between 3 and 15, 3 being the worst and 15 the best)
Impact on patient comfort At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. Numerical Pain Rating Scale (scored between 0 and 10, 0 being "no pain",10 "the worst pain imaginable")
Impact on heart rate At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. Heart rate
Impact on arterial pressure At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. Arterial pressure
Impact on Saturation At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. Saturation
Impact on cerebral tissue oxygenation At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. cerebral tissue oxygenation via NIRS
Impact on cerebral blood flow At T0 before initiation of out-of-bed mobilization, immediately after moving to the edge the bed, immediately after moving to the chair. cerebral blood flow using average velocities on transcranial Doppler
Trial Locations
- Locations (1)
Adéla FOUDHAÏLI
🇫🇷Paris, France