Management of Non Convulsive Status Epilepticus

• Conditions: Status Epilepticus

• Registration Number: NCT03245099
• Lead Sponsor: Assiut University

Brief Summary

Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients

Detailed Description

Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus

Study Timeline

• Status Verified: 2017-08
• Study First Submitted: 2017-08-04
• Study First Submitted QC: 2017-08-07
• Last Update Submitted: 2017-08-07
• Study First Posted: 2017-08-10
• Last Update Posted: 2017-08-10
• Study Start: 2017-12
• Primary Completion: 2018-12
• Study Completion: 2019-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes
• patients presented with un explained psychic or speech disorder
• patients presented with stupor or confusion
• Patients presented with un explained coma

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Exclusion Criteria

• patients with progressive neurological disease
• Patients with severe cerebral anoxia
• Patients with liver or hepatic impairment

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of cured patients	An average of 1 year	Number of cured patients

Trial Locations

Locations (1)

AssiutU; 🇪🇬 Assiut, Egypt