NCT03344744已完成不适用
Circulating and CSF miRNA Profile in Patients With Acute Aneurysmal Subarachnoid Haemorrhage
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Circulating micro RNA concentrations
研究概览
简要总结
The investigators aim to investigate and understand the circulating miRNA profiles after acute aneurysmal subarachnoid haemorrhage and underlying pathological significance.
详细描述
- The investigators aim to investigate the miRNA classifier for delayed cerebral infarction after aneurysmal subarachnoid haemorrhage;
- The investigators aim to investigate the corresponding circulating and CSF miRNA profiles.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aneurysmal subarachnoid hemorrhage patients within the first 72 hours or Healthy volunteers
排除标准
- •Previous neurological diseases such as stroke or dementia
结局指标
主要结局
Circulating micro RNA concentrations
时间窗: Day 3
Serum micro RNA concentrations
次要结局
- Circulating micro RNA change(Days 1,2,3,7)
- Cerebrospinal fluid micro RNA concentrations(Day 1,2,3,7)
- Cerebrospinal fluid micro RNA change(Days 1,2,3,7)
研究者
George KC Wong
Professor(Clinical)
Chinese University of Hong Kong
研究点 (1)
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