NCT03344744CompletedNot Applicable
Circulating and CSF miRNA Profile in Patients With Acute Aneurysmal Subarachnoid Haemorrhage
Chinese University of Hong Kong1 site in 1 country100 target enrollmentStarted: November 30, 2017Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Circulating micro RNA concentrations
Study Overview
Brief Summary
The investigators aim to investigate and understand the circulating miRNA profiles after acute aneurysmal subarachnoid haemorrhage and underlying pathological significance.
Detailed Description
- The investigators aim to investigate the miRNA classifier for delayed cerebral infarction after aneurysmal subarachnoid haemorrhage;
- The investigators aim to investigate the corresponding circulating and CSF miRNA profiles.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 21 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Aneurysmal subarachnoid hemorrhage patients within the first 72 hours or Healthy volunteers
Exclusion Criteria
- •Previous neurological diseases such as stroke or dementia
Outcomes
Primary Outcomes
Circulating micro RNA concentrations
Time Frame: Day 3
Serum micro RNA concentrations
Secondary Outcomes
- Circulating micro RNA change(Days 1,2,3,7)
- Cerebrospinal fluid micro RNA concentrations(Day 1,2,3,7)
- Cerebrospinal fluid micro RNA change(Days 1,2,3,7)
Investigators
George KC Wong
Professor(Clinical)
Chinese University of Hong Kong
Study Sites (1)
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