NCT02756546已完成1 期
Circulating MicroRNAs in Understanding Pathogenesis of Systemic Lupus Erythematosis
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- MicroRNAs expression level
研究概览
简要总结
This study aims to identify the expression signature of miR-181a, miR-196a and miR-21 in plasma of SLE patients and difference in their expression among groups with different systemic lupus erythematosis disease activity index (SLEDAI) scores.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult systemic lupus erythematosis patients
排除标准
- •Patients younger than 18 years, patients with other autoimmune diseases or malignancy.
研究组 & 干预措施
Patients
Active Comparator
SLE patients further divided into mild and severe patients
干预措施: Cyclophosphamide (Drug)
Patients
Active Comparator
SLE patients further divided into mild and severe patients
干预措施: Hydroxychloroquine (Drug)
Patients
Active Comparator
SLE patients further divided into mild and severe patients
干预措施: Hydrocortisone (Drug)
结局指标
主要结局
MicroRNAs expression level
时间窗: 3 months
次要结局
未报告次要终点
研究者
Mona Kortam
Teaching Assistant at faculty of Pharmacy Cairo University
Cairo University
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