The efficacy of Cabergoline in preventing ovarian hyper stimulation in ART program

Phase 3

• Conditions: ovarian hyperstimulation syndrome.; Other obstetric conditions, not elsewhere classified; O94, O99

• Registration Number: IRCT138808271141N7
• Lead Sponsor: Royan Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 130

Inclusion Criteria

Inclusion Criteria: risk of developing OHSS, defined by the development of 20–30 follicles larger than 12 mm in diameter and retrieval of more than 20 oocytes, ovarian stimulation with long protocol

Exclusion Criteria

Coasting cases, age more than 37 years, previous pelvic surgery, Intramural or submucosal myoma sizes > 5 CM, uterine polyps, Smoking, or alcohol addiction

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OHSS occurrence rate and severity of OHSS in two groups. Timepoint: 6 days after embryos transfer(ET). Method of measurement: accordance with the Golan 5 grade system.

Secondary Outcome Measures

Name	Time	Method
Pregnancy and early miscarriage rates. Timepoint: 5 week after embryo transfer until 12 gestational weeks. Method of measurement: Sonography.