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临床试验/NCT06473324
NCT06473324已完成不适用

Association Between Preoperative Persistent Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

Wenbo Ding1 个研究点 分布在 1 个国家目标入组 2,031 人开始时间: 2023年11月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
2,031
试验地点
1
主要终点
Number of Participants with Postoperative Delirium

研究概览

简要总结

This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023. The collected data does not contain any personally identifiable information or breach privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The research aims to investigate the correlation between preoperative blood glucose levels in elderly hip fracture patients and postoperative delirium.

详细描述

A retrospective observational study is planned to explore specific phenomena or associations using electronic medical record data. The collected data does not contain any personally identifiable information or compromise privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The study data is sourced from the electronic medical record system of hospitalized patients and has received approval from the hospital's research center, with ongoing supervision by the hospital's ethics committee. The study aims to investigate the correlation between preoperative blood glucose levels in hip fracture patients and postoperative complications.

The retrospective study aims to collect electronic medical record data spanning from January 2013 to November 2023. The data collection process is consistently monitored and verified by the hospital's ethics committee. Throughout the study, adherence to the ethical principles outlined in the 1964 Helsinki Declaration is ensured, and institutional review board (IRB) approval has been obtained for all aspects of the research.

The study aims to provide valuable evidence-based medicine for clinical practitioners by examining the relationship between preoperative persistent hyperglycemia in elderly hip fracture patients and postoperative delirium. Furthermore, it seeks to offer clinical insights for early identification and intervention management of high-risk postoperative delirium patients (POD).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
60 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who have undergone surgical treatment for hip fractures.

排除标准

  • Multiple or pathological hip fractures.
  • Emergent surgery.
  • Age below 60 years.
  • Incomplete electronic medical records or preoperative blood glucose levels were assessed fewer than two times.
  • Presence of neurological and psychiatric disorders, except dementia.

结局指标

主要结局

Number of Participants with Postoperative Delirium

时间窗: up to 2 months

Postoperative Delirium (POD) manifests as acute cognitive dysfunction and consciousness disorder, characterized by changes in attention or consciousness that cannot be attributed to pre-existing cognitive impairments. Typical symptoms include hallucinations, delusions, agitated behavior, disordered speech, decreased attention, confusion, unclear consciousness, and disrupted sleep-wake cycles. Moreover, POD typically occurs within the first five days after surgery, particularly within the initial 48 hours, and exhibits significant fluctuations.

次要结局

未报告次要终点

研究者

发起方
Wenbo Ding
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Wenbo Ding

Professor

Dandong Central Hospital

研究点 (1)

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