Overcoming Inequalities in Health to Eliminate Hepatitis - Real-World Evidence from a Territory-Wide Cohort
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100,000
- 主要终点
- Safety
研究概览
简要总结
Health inequality in liver diseases including age, gender, ethnicity and socioeconomic status has been increasingly recognised and potentially hinder hepatitis elimination. Health inequality has significant impact to evaluate the impact diagnostic and treatment uptake rates of chronic viral hepatitis on risk of hepatocellular carcinoma (HCC), hepatic event and liver-related death in patients with chronic hepatitis B and/or C. To overcome the limitation of small prospective cohort study of limited recruitment period, retrieving information from the Clinical Data Analysis and Reporting System (CDARS) from Hospital Authority (HA) will be one of the best way to answer these questions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients will be eligible if they have any of these viral markers (HBeAg / HBsAg / HBV DNA / HCV RNA) and/or any of the following diagnosis codes (ICD-9 070-070.9; 348.3, 349.82, 456, 456.2, 456.8, 567.2, 567.8, 570, 571.2, 571.5, 571.6, 572.2, 572.3, 572.4, 789.5) checked or coded in any public hospitals or clinics from 1 January 2000 to 31 March 2024.
排除标准
- •Patients with missing age, gender, ethnicity and socioeconomic status
- •(Subgroup analysis for ethnicity and socioeconomic status) Patients with missing ethnicity and socioeconomic status
- •Serious medical illnesses or malignancy with life expectancy <1 year
结局指标
主要结局
Safety
时间窗: From 1 January 2000 to 31 March 2024
Time from diagnosis of hepatitis to treatment.
次要结局
- Safety(From 1 January 2000 to 31 March 2024)
研究者
Grace Lai Hung Wong
Professor
Chinese University of Hong Kong