ipid-A project

Completed

• Conditions: Topic: Oral & Dental; Subtopic: Oral & Dental Public Health; Disease: All Oral & Dental; Oral Health

• Registration Number: ISRCTN17598447
• Lead Sponsor: Peninsula Dental Social Enterprise CIC

Brief Summary

1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/30543027 (added 22/01/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-01-08
• Study Completion: 2015-06-30
• Last Update Posted: 11 February 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Healthy (PD <4 mm, no evidence of attachment and bone loss, and <10% of sites with BOP)
2. Chronic periodontitis (presence of 1/3 bone loss or more and presence of 6 mm pocket or more, with evidence of attachment loss at 2 or more teeth per quadrant and evidence of generalized bleeding)

Exclusion Criteria

1. Systemic chronic diseases
2. Acute medical interventions or diseases 4 weeks before baseline
3. Pregnancy
4. Antibiotics 6 months before intake and or repeated use of NSAID's medications 4 weeks before intake

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in subginigval lipid-A profile; Timepoint(s): 3 months after completion of periodontal therapy