跳至主要内容
临床试验/NCT05092087
NCT05092087已完成不适用

Effects of Nutritional Counseling Regularity on the Risk of Cardiovascular Diseases

Taipei Medical University1 个研究点 分布在 1 个国家目标入组 129 人开始时间: 2021年4月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
129
试验地点
1
主要终点
The concentration of blood insulin

研究概览

简要总结

This study aims to investigate the frequency of personalized nutrition counseling's effect on individual cardiovascular risk factors. The study collected 110 to 150 cases data, including a regular blood test, blood glucose, blood lipid, liver panel, and inflammatory factors. The enrolled cases were classified into two groups according to the subjects' duration of consultation: those who completed the consultation and subsequent tests in >24 weeks were in the control group, whereas those who completed the consultation and subsequent tests in <24 weeks were in the test group. The effectiveness of nutrition consultation toward managing cardiovascular disease risk factors and its correlation with the subjects' frequency of following the consultations was analyzed using the pre- and post-consultation data. It was found that personalized nutrition consultation significantly improved the subjects' risk factors of cardiovascular diseases, and that the treatment group showed a greater improvement than the control group which who require over 24 weeks to complete all consultation sessions.

详细描述

The most of interventional studies on nutrition consultation have generally emphasized on the extent to which the diet composition can prevent chronic diseases or provide improvement. Although dietitians play an important role in health education for the primary prevention of chronic disease, their individuals dietary consultation results are mostly focused on weight loss and blood glucose control. However, the effectiveness of nutrition consultation on the prevention of chronic diseases, such as hyperlipidemia, hypertension and cardiovascular diseases, has few been studied. The effectiveness of dietary instructions provided to individuals by dietitians in primary health care institutes is yet to be validated with significant evidence. In addition, nutrition consultation methods, processes, and influencing factors on its results are seldom discussed. Therefore, this study aims to investigate the frequency of personalized nutrition counseling's effect on individual cardiovascular risk factors. The study collected1 10 to 150 cases data who aimed to prevent or improve chronic diseases and had completed eight times individualized nutrition consultations from Bon Vivant Health Lifestyle Management Center, and the pre- and post-consultation data, including a regular blood test, blood glucose, blood lipid, liver panel, and inflammatory factors, will be analyzed. Blood were drawn before and after the first and the last time consultation for biochemical tests; blood pressure and body composition was also measured for comparison. The enrolled cases will be classified into two groups according to the subjects' duration of consultation: those who completed the consultation and subsequent tests in >24 weeks were in the control group, whereas those who completed the consultation and subsequent tests in <24 weeks were in the test group. The effectiveness of nutrition consultation toward managing cardiovascular disease risk factors and its correlation with the subjects' frequency of following the consultations was analyzed using the pre- and post-consultation data. It was found that personalized nutrition consultation significantly improved the subjects' risk factors of cardiovascular diseases, and that the treatment group showed a greater improvement than the control group which who require over 24 weeks to complete all consultation sessions.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Anyone of follow: body mass index > 24 systolic blood pressure > 120 mmHg diastolic blood pressure > 80 mmHg triglyceride > 150 mg/dL fasting blood glucose >100 mg/dL

排除标准

  • Mental problem
  • unable to do the measurement of body composition
  • incomplete the nutritional counseling program

结局指标

主要结局

The concentration of blood insulin

时间窗: within one week after the intervention

blood insulin in mg/dL

body mass index

时间窗: immediately after the intervention

body mass index in kg/m\^2

The concentration of blood urinary nitrogen (BUN)

时间窗: within one week after the intervention

BUN in mg/L

The concentration of blood globulin

时间窗: within one week after the intervention

blood uric acid in mg/dL

The concentration of blood high sensitive C-reactive protein

时间窗: within one week after the intervention

blood high sensitive sensitive C-reactive protein in mg/L

The concentration of blood high density lipoprotein-cholesterol-cholesterol

时间窗: within one week after the intervention

blood high density lipoprotein-cholesterol in mg/dL

The concentration of blood total cholesterol

时间窗: within one week after the intervention

blood total cholesterol in mg/dL

blood HbA1C

时间窗: within one week after the intervention

blood HbA1C in percentage

The concentration of blood total protein

时间窗: within one week after the intervention

blood uric acid in mg/dL

height

时间窗: immediately after the intervention

height in meters

The concentration of blood triglyceride

时间窗: baseline, pre-intervention

blood triglyceride in mg/dL

The activity of blood alanine aminotransferase

时间窗: within one week after the intervention

blood alanine aminotransferase in U/L

body weight

时间窗: immediately after the intervention

body weight in kilograms

body fat

时间窗: immediately after the intervention

body fat in ratio

The concentration of blood low density lipoprotein-cholesterol

时间窗: within one week after the intervention

blood blood low density lipoprotein-cholesterol in mg/dL

The concentration of blood fasting glucose

时间窗: within one week after the intervention

blood fasting glucose in mg/dL

The activity of blood aspartate aminotransferase

时间窗: within one week after the intervention

blood aspartate aminotransferase in U/L

The concentration of blood creatinine

时间窗: within one week after the intervention

BUN in mg/dL

The concentration of blood uric acid

时间窗: within one week after the intervention

blood uric acid in mg/dL

The concentration of blood albumin

时间窗: within one week after the intervention

blood uric acid in mg/dL

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验