compare the effectiveness of predicting success of taking out the patient from Ventilator support by measuring thickness of muscle used for respiration by ultrasound scan with Indices calculated from values obtained from ventilator

Not Applicable

• Conditions: Health Condition 1: J00-J99- Diseases of the respiratory system

• Registration Number: CTRI/2022/09/045524
• Lead Sponsor: Jawarhalal institute of Postgraduate Medical education and Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) Age more than 18 years

2) Mechanical ventilation of at least 48 hours

3) Patient should met the following criteria for readiness of weaning:

�Oxygenation status: FiO2 <0.5 with PEEP less than or equal to 8 cm H2O & paO2/FiO2 >200

�Ventilation status: Respiratory rate less than or equal to 30/min & paCO2 of <45 mmHg

�Stable hemodynamics

�Intact mentation

�Minimal secretion and effective cough

Exclusion Criteria

1) Known Neuromuscular disorder

2) Known case of diaphragmatic paralysis

3) Tracheostomized patients

4) Increased Intraabdominal Pressure

5) Phrenic Nerve Palsy

6) Obstetric antenatal patients

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess and compare the effectiveness of predicting weaning success of DTF with CORE index and Integrated weaning index <br/ ><br> <br/ ><br>Timepoint: After 48 hours of initiation of mechanical ventilation and with pressure support of 8 and 5 cmH2o during weaning <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
To calculate the cut-off value for optimal DTF to succeed weaning at different time points after initiation of mechanical ventilationTimepoint: 48 hours, 5th day, 7 th day, 10 and 14 th day