se of diaphragm thickening fraction combined with rapid shallow breathing index for predicting weaning success from mechanical ventilator in COPD patients
Not Applicable
Recruiting
- Conditions
- COPD patientsUsing Mechanical VentilationMedicine Department
- Registration Number
- TCTR20201103003
- Lead Sponsor
- Faculty of medicine, Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
1.Age ≥ 40 years
2.COPD patients, Diagnosis by spirometry recorded post bronchodilator FEV1/FVC < 70%
3.Respiratory failure with mechanical ventilation more than 24 hours,
4.Ability to tolerate SBT for 1 hour before ultrasound
5.Patient readiness for weaning must have met all criteria: using FIO2 < 0.5, and PEEP ≤ 5 cmH2O, PaO2/FIO2 > 200, respiratory rate ≤ 30 breaths/minute, stable hemodynamic (absence or low dose vasopressors required), good consciousness and cooperative, minimal secretion and effectiveness of cough
Exclusion Criteria
1.The patients or relatives of the patients refused to participate
2.Known case of Neuromuscular weakness
3.On tracheostomy tube
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effectiveness of diaphragmatic thickening fraction combined with rapid shallow breathing index 48 hours after spontaneous breathing trial Point-of-care ultrasound
- Secondary Outcome Measures
Name Time Method /A N/A N/A