临床试验/NCT02948387

NCT02948387Unknown不适用

Antibiotic Prophylaxis for Type II and III Open Fractures: a Retrospective Chart Review

Olayemi Osiyemi MD1 个研究点分布在 1 个国家目标入组 50 人开始时间: 2016年11月最近更新: 2016年10月28日

适应症

试验速览

阶段: 不适用
发起方
入组人数: 50
试验地点: 1
主要终点: Rate of fracture site infections

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Determine if antibiotic prophylaxis with intravenous cephalosporin and aminoglycoside in patients with Type II and II open fractures is safe and effective.

详细描述

Determine the safety and efficacy of antibiotic prophylaxis in type II and II open fractures when using IV Cephalosporin and aminoglycoside.
Identify the incidence of acute kidney injury.
Identify the type and number of associated infections
Identify the antibiotic resistance profile noted
Identify any secondary infections at sites other than the fracture site

研究设计

研究类型: Observational
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Male or Female >= 18 years old
•Patients are diagnosed with a Type II or III open fracture

排除标准

•Prior to treatment, report of an allergy to beta-lactam or aminoglycoside antibiotics
•pregnancy
•did not receive 72 hours of IV antibiotic prophylaxis with 1st or 2nd generation cephalosporin and either gentamicin or tobramycin
•receiving ongoing inpatient care

结局指标

主要结局

Rate of fracture site infections

时间窗: 30 days

number of infections

次要结局

Incidence of acute renal injury(30 days)
number of secondary infections at site other than fracture sites(30 days)
type of bacteria infection(30 days)
resistance trend in patients with infections(30 days)

研究者

发起方

Olayemi Osiyemi MD

申办方类型

Other

责任方

Sponsor Investigator

主要研究者

Olayemi Osiyemi MD

President

Triple O Research Institute PA

研究点 (1)

Loading locations...

相似试验

Unknown

4 期

Antibiotic Prophylaxis in Open FracturesOpen Fractures

NCT02937181Olayemi Osiyemi MD50

Unknown

2 期

Efficacy Assessment of Two Antibiotic Prophylaxis Regimens in Oral and Maxillofacial Trauma SurgeryFacial Fractures

NCT01993134Universidade Federal do Rio Grande do Norte75

已完成

4 期

Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic LesionsPancreatic Cystic Lesion

NCT02261896Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau226

终止

4 期

Antibiotic Prophylaxis in Laparoscopic CholecystectomyCholelithiasis

NCT01888822University of Roma La Sapienza138

已完成

不适用

To study whether giving long duration prophylactic antibiotics in patients with isolated blunt chest injuries managed with intercostal tube drainage (ICD) has any role in preventing ICD related infectious complications.

CTRI/2019/10/021704Department of Trauma surgery120