Study comparing combination of three drugs, sevoflurane with fentanyl and desflurane with fentanyl(drugs used for giving anesthesia)based on time taken for coming out of anesthesia after stopping their use.

Not Applicable

Completed

• Conditions: Health Condition 1: null- STABLE

• Registration Number: CTRI/2018/04/012993
• Lead Sponsor: Max Superspeciality hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-03-31
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 70

Inclusion Criteria

1.Patients undergoing ambulatory surgery

2.Age between 18-60 years

3.ASA grade 1 and 2

4.Expected duration of surgery less than 90 minutes

5.Patient with adequate mouth opening as defined by Mallampati scores(I &II)

6.Patient with adequate NPO status(as per ASA guidelines)

Exclusion Criteria

1.Patient refusal to participate in the study

2.Patients <18yrs or >60 years of age

3.Pregnancy

4.ASA 3 and 4 patients

5.Patients with full stomach

6.Patients taking CNS depressants

7.Patients with psychiatric disorders

8.Chronic opioid or corticosteroid use

9.Patients with liver or renal disease

10.Obese patients ( Body mass index >35kg/m2)

11.Patients with upper airway morbidity (symptoms suggestive of URTI including cough, scratchy throat and hoarseness).

12.Patients with Mallampati scores III &IV

13.H/o of asthma

14.H/o of gastritis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Total time duration for awakening after discontinuation of volatile anaesthetic agent. <br/ ><br>2.Incidence of cough determined through scores after discontinuation of the volatile anaesthetic agent. <br/ ><br>Timepoint: 1.Specific time when subject spontaneously opens his eyes after discontinuation of anesthetic agent <br/ ><br>2.Incidence of cough determined after patient being shifted to PACU. <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
1.Total duration of time to follow commands by protruding tongue after discontinuation of volatile anaesthetic agent. <br/ ><br>2.Total duration of time to develop coherent speech after discontinuation of volatile anaesthetic agent. <br/ ><br>Timepoint: Time duration after discontinuation of volatile anaesthetic agent.