NCT00771940已完成1 期
Peripheral Metabolic Effects of Intra Arterial Ghrelin Infusion in Healthy Controls
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Plasma levels of glucose
研究概览
简要总结
The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI < 27 kg/m2
- •Written informed consent
排除标准
- •Any disease including epilepsy
- •Any use of medications (excl. paracetamol)
- •Present or previous malignancy
- •Alcohol dependency
- •Allergy to any trial medication
研究组 & 干预措施
Ghrelin
Active Comparator
干预措施: Ghrelin (Drug)
结局指标
主要结局
Plasma levels of glucose
时间窗: During study day
次要结局
- Insulin signaling(Study day)
- Serum levels of fatty acids(Study day)
研究者
研究点 (1)
Loading locations...
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