NCT01062529已完成不适用
Peripheral Metabolic Effects of Intra Arterial Somatostatin Infusion in Healthy Controls
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Plasma levels of glucose
研究概览
简要总结
The aim of this study is to investigate peripheral effects of Somatostatin on glucose metabolism and growth hormone (GH) signalling in healthy men. Eight subjects will be enrolled. The hypothesis is that Somatostatin infusion reverses insulin resistance caused by GH.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI < 27 kg/m2
- •Written informed consent
排除标准
- •Any disease
- •Any use of medications
- •Present or previous malignancy
- •Alcohol dependency
- •Allergy to trial medication
研究组 & 干预措施
somatostatin
Experimental
干预措施: Somatostatin (Drug)
结局指标
主要结局
Plasma levels of glucose
时间窗: 3 months
次要结局
- GH signalling(one year)
- Serum levels of free fatty acids (FFA)(one year)
研究者
研究点 (1)
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