Changes in host gene expression to differentiate between systemic inflammation and infection after major surgery (PAX study)

• Conditions: infection; Sepsis; 10004018

• Registration Number: NL-OMON56862
• Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 July 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

A subject must meet all of the following criteria: Age >18 years, major
noncardiac surgery with infection risk >20% (e.g., pancreatic surgery,
hyperthermic intraperitoneal chemotherapy (HIPEC) surgery, colon resection).

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study: Age <18 years, emergency surgery, inability
to provide informed consent.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Postoperative infection </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>SIRS, sepsis </p><br>