The altered gene expression profiles of leprosy causing bacteria and the human host in patients with chronic and recurrent type 2 lepra reaction.
Not Applicable
- Conditions
- Health Condition 1: A305- Lepromatous leprosy
- Registration Number
- CTRI/2023/07/054861
- Lead Sponsor
- Indian Association of Dermatologists, Venereologists & Leprologists (IADVL)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All the cases of severe chronic and recurrent erythema nodosum leprosum, defined as ENLIST ENL Severity Scale (EESS) score =9, who will present to the OPD of the Dermatology department
Exclusion Criteria
i.Patients with known immunodeficiency or on immunosuppressive drugs within last month
ii.Patients not willing to give consent
iii.Pregnancy and lactation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To characterize the transcriptome profiles of host-bacilli in patients with chronic & recurrent erythema nodosum leprosumTimepoint: April 2025
- Secondary Outcome Measures
Name Time Method To observe the association between antimicrobial resistance & the <br/ ><br>presence of chronic & recurrent erythema nodosum leprosumTimepoint: April 2025