COMPARATIVE STUDY OF INTRATHECAL ISOBARIC ROPIVACAINE (0.75%) WITH BUPRENORPHINE AND ISOBARIC ROPIVACAINE (0.75%) WITH CLONIDINE IN PATIENTS UNDERGOING LOWER LIMB AND LOWER ABDOMINAL SURGERIES UNDER SUBARACHNOID BLOCK: A Prospective Randomised Double- blind study ?
Phase 1
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/02/062242
- Lead Sponsor
- Chettinad academy research and education
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American Society of Anesthesiologists (ASA) grade I-III
2. Age group between 18-60 years of both sexes.
3. Scheduled for Elective and emergency lower limb orthopedic AND ABDOMINAL surgeries under Spinal Anaesthesia.
Exclusion Criteria
1. Patient refusal
2. History of allergy to study drugs
3. Post spinal surgeries, Spinal Deformities, skin sepsis in lumbar region, patients with pre-existing neurological disorders.
4. Coagulopathy, Dysrhythmia
5. Major Hepatic, Renal and Cardiovascular Dysfunction
6. BMI >35, Height <140cm
7. Surgeries involving major blood loss
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TO COMPARE THE DURATION OF ANALGESIA from baselineTimepoint: TO COMPARE THE DURATION OF ANALGESIA baseline to 3 hours
- Secondary Outcome Measures
Name Time Method TO COMPARE THE ADDITIONAL ANALGESIC REQUIREMENT IN FIRST 24 HOURSTimepoint: FIRST 24 HOURS