Breast conserving surgery using Accelerated Partial Breast Irradiation in Elderly Patients with breast cancer.
Recruiting
- Conditions
- Early stage breast cancer in elderly female patients.age >=60 yearT1/2 N0 M0Oudere vrouwen met borstkanker in een vroeg stadium leeftijd >= 60 jaar
- Registration Number
- NL-OMON26007
- Lead Sponsor
- Radiotherapiecentrum West
- Brief Summary
Intraoperative radiotherapy during breast conserving surgery; a study on 1822 cases treated with electrons. Veronesi et al, B4reast Cancer Res Treat. 2010 Nov;124(1):141-51. Epub 2010 Aug 15. PMID: 20711810
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 710
Inclusion Criteria
1. Histological confirmed breast cancer (DCIS and invasive) subtypes;
2. T1 as determined by ultrasound;
Exclusion Criteria
1. Patients not eligible / fit for lumpectomy and sentinel node procedure;
2. T2 smaller than 30 mm and triple negative or Her2neu +++;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method oco regional tumor control at 5 years.
- Secondary Outcome Measures
Name Time Method 1. (Loco regional) tumor control;<br /><br>2. Side effects;<br /><br>3. (Inter current) death;<br /><br>4. Geriatric condition (questionnaires);<br /><br>5. Co-morbidity and usage of medication.