Effect of Procrit (Epoetin Alfa) on Preventing Delayed Graft Function After Deceased Donor Renal Transplantation
Phase 4
Completed
- Conditions
- Delayed Graft Function
- Registration Number
- NCT00425126
- Lead Sponsor
- West Penn Allegheny Health System
- Brief Summary
Delayed graft function (DGF) is a major complication following deceased donor renal transplantation. The surgical procedure of harvesting a kidney from a cadaveric donor and implanting the kidney into the recipient inevitably causes some amount of injury. While not always clinically significant, anywhere from 10-50% of transplant patients may develop DGF. Ongoing research in animal models has demonstrated benefit with administration of erythropoietin. The investigators propose to study the effect of Procrit(Epoetin Alfa) on delayed graft function in subjects undergoing kidney transplantation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
- Patients presenting for kidney transplantation
- Age > 18
- Deceased donor kidney transplant
Exclusion Criteria
- History of thrombosis or hypercoagulable state
- Receiving Coumadin or Heparin
- Hemoglobin >=14 g/dl
- Uncontrolled hypertension
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Decrease in Delayed Graft Function
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Allegheny General Hospital
🇺🇸Pittsburgh, Pennsylvania, United States