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临床试验/NCT00425126
NCT00425126已完成4 期

Effect of Procrit(Epoetin Alfa) on Preventing Delayed Graft Function After Deceased Donor Renal Transplantation

West Penn Allegheny Health System2 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2007年2月最近更新:
适应症
相关药物

试验速览

阶段
4 期
状态
已完成
入组人数
76
试验地点
2
主要终点
Decrease in Delayed Graft Function

研究概览

简要总结

Delayed graft function (DGF) is a major complication following deceased donor renal transplantation. The surgical procedure of harvesting a kidney from a cadaveric donor and implanting the kidney into the recipient inevitably causes some amount of injury. While not always clinically significant, anywhere from 10-50% of transplant patients may develop DGF. Ongoing research in animal models has demonstrated benefit with administration of erythropoietin. The investigators propose to study the effect of Procrit(Epoetin Alfa) on delayed graft function in subjects undergoing kidney transplantation.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Double

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients presenting for kidney transplantation
  • Age > 18
  • Deceased donor kidney transplant

排除标准

  • History of thrombosis or hypercoagulable state
  • Receiving Coumadin or Heparin
  • Hemoglobin >=14 g/dl
  • Uncontrolled hypertension

结局指标

主要结局

Decrease in Delayed Graft Function

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (2)

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