Lumigan Versus Cosopt
Phase 4
Completed
- Conditions
- Open-Angle Glaucoma
- Registration Number
- NCT00273455
- Lead Sponsor
- Pharmaceutical Research Network
- Brief Summary
To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
- adults with a diagnosis of bilateral open-angle glaucoma including: primary, pigment dispersion or exfoliation in both eyes
- on no therapy the intraocular pressure should be 22-29 mm Hg inclusive at the 8:00 AM measurement
- visual acuity should be 20/200 or better in each eye
Exclusion Criteria
- historical failure to respond to topical beta-blockers in a clinically meaningful manner
- any contraindication to study medications
- any anticipated change, or modification in the 6 weeks prior to Visit 1, in systemic hypertensive therapy during the trial
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Houston Eye Associates
🇺🇸Houston, Texas, United States
Taustine Eye Center
🇺🇸Louisville, Kentucky, United States
Glaucoma Consultants & Center for Eye Research, PA
🇺🇸Mt. Pleasant, South Carolina, United States