NCT00273455已完成4 期
Lumigan Versus Cosopt
Pharmaceutical Research Network6 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2006年1月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 34
- 试验地点
- 6
研究概览
简要总结
To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adults with a diagnosis of bilateral open-angle glaucoma including: primary, pigment dispersion or exfoliation in both eyes
- •on no therapy the intraocular pressure should be 22-29 mm Hg inclusive at the 8:00 AM measurement
- •visual acuity should be 20/200 or better in each eye
排除标准
- •historical failure to respond to topical beta-blockers in a clinically meaningful manner
- •any contraindication to study medications
- •any anticipated change, or modification in the 6 weeks prior to Visit 1, in systemic hypertensive therapy during the trial
研究者
研究点 (6)
Loading locations...
相似试验
已完成
4 期
Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide 2% on Monotherapy With Latanoprost in Patients With Elevated Intra-ocular PressureGlaucomaNCT00906594University of Sao Paulo56
已完成
不适用
Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma PatientsOpen Angle GlaucomaNCT01304264Lithuanian University of Health Sciences35
已完成
2 期
Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric GlaucomaChildhood GlaucomaNCT01527682Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia37
已完成
1 期
Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact LensesGlaucomaNCT02852057University of Florida2
已完成
2 期
COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED)GlaucomaNCT00832377Merck Sharp & Dohme LLC37