A study used to determine in which among the two methods of fastest orthodontic tooth movement have more amount of root resorption

Not yet recruiting

Conditions: Other specified disorders of teethand supporting structures,

Registration Number: CTRI/2021/05/033657

Lead Sponsor: DR DEEPAK E R

Brief Summary: The increased treatment time required for orthodontic therapy is one of the major causes for the increase in the risk of root resorption. Shorter duration of orthodontic treatment is the need of the hour in current practice as huge number of adult patients demand results within a short span of time. As a result, there is an increased number of studies focusing on methods that accelerate orthodontic tooth movement.

Several noninvasive or invasive techniques have been proposed clinically or experimentally for accelerating orthodontic tooth movement. The noninvasive techniques include (a) biomechanical approach such as the self-ligation brackets, (b) physiological approach such as the direct electric current stimulation, the low level laser therapy, vibration or photomodulation and (c) pharmacological approach such as the injection of prostaglandin or relaxin.

Keser and Dibart, introduced the Piezocision technique, a novel minimally invasive technique for accelerated tooth movement. One of the recently used local agents to accelerate the rate of orthodontic tooth movement is platelet-rich plasma (PRP). PRP is defined as an autologous concentration of platelets in a minute volume of plasma. Hence the study is conducted to assess and compare the amount of root resorption in Piezocision and PRP induced accelerated tooth movement.

Hence the need for the present study is to -

1.To assess the rate of root resorption with Piezocision induced accelerated orthodontic tooth movement.

2.To assess the rate of root resorption with Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.

3.To compare the rate of root resorption between Piezocision induced and Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.

4.To draw the clinical inferences from above.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 20

Inclusion Criteria

1.Angleâ€™s class I malocclusion indicated for bilateral maxillary first premolar extraction.
2.Male and female patients between the age group of 18 and 45 years.
3.Patients with no clinical signs of periodontal diseases.
4.Patients with no gingivitis or untreated caries 5.Patients with no history of periodontal therapy.

Exclusion Criteria

1.Previous history of any orthodontic or orthopedic treatment 2.Any bone pathology, ankylosed teeth.
3.Patients taking drugs modifying normal bone physiology (i.e., bisphosphonates) on or before a period of 3 months.
4.Long term use ofanti-biotics, phenytoin, cyclosporine, anti-inflammatory drugs, systemic corticosteroids and calcium channel blockers.
5.Smokers 6.Patients with evidence of bone loss.
7.Patient having a pacemaker or any other active implant.
8.Patients who have undergone periodontal treatment within three months of baseline examination.
9.Systemic disorder that could influence periodontal health.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Assess the rate of root resorption with Piezocision induced accelerated orthodontic tooth movement.	1 month and 6 month
2.Assess the rate of root resorption with Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.	1 month and 6 month

Secondary Outcome Measures

Name	Time	Method
Compare the rate of root resorption between Piezocision induced and Platelet rich plasma (PRP) induced accelerated orthodontic tooth movement.	1 month and 6 month

Trial Locations

Locations (1): COORG INSTITUTE OF DENTAL SCIENCES
🇮🇳
Kodagu, KARNATAKA, India
COORG INSTITUTE OF DENTAL SCIENCES
🇮🇳Kodagu, KARNATAKA, India
DR DEEPAK E R
Principal investigator
8248727906
dr.erdeepak@gmail.com